5GIO
Crystal structure of box C/D RNP with 12 nt guide regions and 13 nt substrates
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, M (A, B, K) | C/D box methylation guide ribonucleoprotein complex aNOP56 subunit | polymer | 388 | 44168.5 | 3 | UniProt (A0A0E3MJI1) Pfam (PF21572) Pfam (PF01798) UniProt (by SIFTS) (Q97ZH3) | Sulfolobus solfataricus | |
| 2 | B, E, N (C, D, L) | 50S ribosomal protein L7Ae | polymer | 130 | 14075.3 | 3 | UniProt (A0A0E3JZF7) Pfam (PF01248) UniProt (by SIFTS) (P55858) | Sulfolobus solfataricus | Ribosomal protein L8e |
| 3 | C, F, O (E, F, M) | Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase | polymer | 232 | 26439.4 | 3 | UniProt (A0A0E3JUC9) Pfam (PF01269) UniProt (by SIFTS) (P58032) | Sulfolobus solfataricus | |
| 4 | G, H, K (G, H, N) | C/D RNA | polymer | 40 | 12852.7 | 3 | Sulfolobus solfataricus | ||
| 5 | I, J, L (I, J, O) | substrate | polymer | 13 | 4181.6 | 3 | Sulfolobus solfataricus | ||
| 6 | P, Q, R (E, F, M) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 3 | Chemie (SAH) PubChem (16760024) PubChem (193) PubChem (13792) PubChem (177678424) PubChem (189149) PubChem (439155) PubChem (25210495) PubChem (21125603) PubChem (44361184) PubChem (25203782) PubChem (46936206) PubChem (50989525) PubChem (51380914) PubChem (52224398) PubChem (57544532) PubChem (52224400) PubChem (59046843) PubChem (59170628) PubChem (59576228) PubChem (66805708) PubChem (5284331) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (71170554) PubChem (13231890) PubChem (6419189) PubChem (118374891) PubChem (118560068) PubChem (126969526) PubChem (129105892) PubChem (164157219) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525) |
Sequence modifications
A, B, K: 4 - 380 (UniProt: A0A0E3MJI1)
C, D, L: 6 - 130 (UniProt: A0A0E3JZF7)
E, F, M: 3 - 232 (UniProt: A0A0E3JUC9)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Val 2 | - | expression tag |
| Lys 3 | - | expression tag |
| His 381 | - | expression tag |
| His 382 | - | expression tag |
| His 383 | - | expression tag |
| His 384 | - | expression tag |
| His 385 | - | expression tag |
| His 386 | - | expression tag |
| His 387 | - | expression tag |
| His 388 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Asp 2 | - | expression tag |
| Ala 3 | - | expression tag |
| Met 4 | - | expression tag |
| Ser 5 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Ala 2 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 15 |
| Total formula weight | 305152.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1153.2 | |
| All* | Total formula weight | 306305.5 |
