5GIO
Crystal structure of box C/D RNP with 12 nt guide regions and 13 nt substrates
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, K | C/D box methylation guide ribonucleoprotein complex aNOP56 subunit | polymer | 388 | 44168.5 | 3 | UniProt (A0A0E3MJI1) Pfam (PF21572) Pfam (PF01798) UniProt (by SIFTS) (Q97ZH3) In PDB | Sulfolobus solfataricus | |
2 | C, D, L | 50S ribosomal protein L7Ae | polymer | 130 | 14075.3 | 3 | UniProt (A0A0E3JZF7) Pfam (PF01248) UniProt (by SIFTS) (P55858) In PDB | Sulfolobus solfataricus | Ribosomal protein L8e |
3 | E, F, M | Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase | polymer | 232 | 26439.4 | 3 | UniProt (A0A0E3JUC9) Pfam (PF01269) UniProt (by SIFTS) (P58032) In PDB | Sulfolobus solfataricus | |
4 | G, H, N | C/D RNA | polymer | 40 | 12852.7 | 3 | Sulfolobus solfataricus | ||
5 | I, J, O | substrate | polymer | 13 | 4181.6 | 3 | Sulfolobus solfataricus | ||
6 | E, F, M | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 3 | Chemie (SAH) |
Sequence modifications
A, B, K: 4 - 380 (UniProt: A0A0E3MJI1)
C, D, L: 6 - 130 (UniProt: A0A0E3JZF7)
E, F, M: 3 - 232 (UniProt: A0A0E3JUC9)
PDB | External Database | Details |
---|---|---|
Met 1 | - | initiating methionine |
Val 2 | - | expression tag |
Lys 3 | - | expression tag |
His 381 | - | expression tag |
His 382 | - | expression tag |
His 383 | - | expression tag |
His 384 | - | expression tag |
His 385 | - | expression tag |
His 386 | - | expression tag |
His 387 | - | expression tag |
His 388 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Met 1 | - | initiating methionine |
Asp 2 | - | expression tag |
Ala 3 | - | expression tag |
Met 4 | - | expression tag |
Ser 5 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Met 1 | - | initiating methionine |
Ala 2 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 15 |
Total formula weight | 305152.2 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 1153.2 | |
All* | Total formula weight | 306305.5 |