5GHW
Crystal structure of broad neutralizing antibody 10E8 with long epitope bound
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | H | FAB 10E8 HEAVY CHAIN | polymer | 239 | 25648.7 | 1 | Homo sapiens | ||
2 | L | FAB 10E8 LIGHT CHAIN | polymer | 216 | 23152.6 | 1 | Homo sapiens | ||
3 | P | Endogenous retrovirus group K member 8 Env polyprotein | polymer | 36 | 4623.7 | 1 | UniProt (G3DED6) UniProt (by SIFTS) (P04578) In PDB | Human immunodeficiency virus 1 | Endogenous retrovirus group K member 113 Env polyprotein,Endogenous retrovirus group K member 13-1 Env polyprotein,Endogenous retrovirus group K member 18 Env polyprotein,Endogenous retrovirus group K member 19 Env polyprotein,Endogenous retrovirus group K member 21 Env polyprotein,Endogenous retrovirus group K member 24 Env polyprotein,Endogenous retrovirus group K member 25 Env polyprotein,Endogenous retrovirus group K member 6 Env polyprotein,Endogenous retrovirus group K member 7 Env polyprotein,Endogenous retrovirus group K member 9 Env polyprotein,Envelope glycoprotein gp160 |
4 | H, L | PHOSPHATE ION | non-polymer | 95.0 | 7 | Chemie (PO4) | |||
5 | water | water | 18.0 | 132 | Chemie (HOH) |
Sequence modifications
P: 666 - 690 (UniProt: G3DED6)
PDB | External Database | Details |
---|---|---|
Lys 660 | - | expression tag |
Lys 661 | - | expression tag |
Lys 662 | - | expression tag |
Lys 663 | - | expression tag |
Asp 664 | - | expression tag |
Lys 665 | - | expression tag |
Lys 691 | - | expression tag |
Lys 692 | - | expression tag |
Lys 693 | - | expression tag |
Lys 694 | - | expression tag |
Lys 695 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 53425.0 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 664.8 | |
All* | Total formula weight | 54089.8 |