5GAM
Foot region of the yeast spliceosomal U4/U6.U5 tri-snRNP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (U) | U5 snRNA | polymer | 178 | 57138.7 | 1 | GenBank (807071959) | Saccharomyces cerevisiae (Baker's yeast) | |
| 2 | B (A) | Pre-mRNA-splicing factor 8 | polymer | 735 | 85826.1 | 1 | UniProt (P33334) Pfam (PF08082) Pfam (PF08083) | Saccharomyces cerevisiae (Baker's yeast) | Prp8, N-terminal domain |
| 3 | C (C) | Pre-mRNA-splicing factor SNU114 | polymer | 1008 | 114132.1 | 1 | UniProt (P36048) Pfam (PF16004) Pfam (PF00009) Pfam (PF03764) Pfam (PF00679) | Saccharomyces cerevisiae (Baker's yeast) | 114 kDa U5 small nuclear ribonucleoprotein component,Growth inhibitory protein 10,Snu114 |
| 4 | D (W) | U6 snRNA, 5' end | polymer | 31 | 9928.9 | 1 | Saccharomyces cerevisiae (Baker's yeast) | ||
| 5 | E (b) | Small nuclear ribonucleoprotein-associated protein B | polymer | 196 | 22427.0 | 1 | UniProt (P40018) Pfam (PF01423) | Saccharomyces cerevisiae (Baker's yeast) | snRNP-B,Sm protein B,SmB, U5 SmB |
| 6 | F (e) | Small nuclear ribonucleoprotein E | polymer | 94 | 10385.1 | 1 | UniProt (Q12330) Pfam (PF01423) | Saccharomyces cerevisiae (Baker's yeast) | snRNP-E,Sm protein E,SmE, U5 SmE |
| 7 | G (f) | Small nuclear ribonucleoprotein F | polymer | 86 | 9669.9 | 1 | UniProt (P54999) Pfam (PF01423) | Saccharomyces cerevisiae (Baker's yeast) | snRNP-F,Sm protein F,SmF |
| 8 | H (g) | Small nuclear ribonucleoprotein G | polymer | 77 | 8490.8 | 1 | UniProt (P40204) Pfam (PF01423) | Saccharomyces cerevisiae (Baker's yeast) | snRNP-G,Sm protein G,SmG |
| 9 | I (x) | Unknown polypeptide | polymer | 18 | 1549.9 | 1 | Saccharomyces cerevisiae (Baker's yeast) | ||
| 10 | J (d) | Small nuclear ribonucleoprotein Sm D3 | polymer | 101 | 11240.1 | 1 | UniProt (P43321) Pfam (PF01423) | Saccharomyces cerevisiae (Baker's yeast) | Sm-D3,snRNP core protein D3, U5 SmD3 |
| 11 | K (h) | Small nuclear ribonucleoprotein Sm D1 | polymer | 146 | 16296.8 | 1 | UniProt (Q02260) Pfam (PF01423) | Saccharomyces cerevisiae (Baker's yeast) | Sm-D1,snRNP core protein D1, U5 SmD1 |
| 12 | L (j) | Small nuclear ribonucleoprotein Sm D2 | polymer | 110 | 12876.1 | 1 | UniProt (Q06217) Pfam (PF01423) | Saccharomyces cerevisiae (Baker's yeast) | Sm-D2,snRNP core protein D2, SmD2 |
| 13 | M (C) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) |
Sequence modifications
C: 1 - 1008 (UniProt: P36048)
| PDB | External Database | Details |
|---|---|---|
| Ser 530 | Glu 530 | conflict |
| Lys 531 | Asp 531 | conflict |
| Thr 532 | Asp 532 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 359961.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 523.2 | |
| All* | Total formula weight | 360484.7 |
