5G18
Direct Observation of Active-site Protonation States in a Class A beta lactamase with a monobactam substrate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | BETA-LACTAMASE CTX-M-97 | polymer | 262 | 28117.8 | 1 | UniProt (E1ANH6) UniProt (by SIFTS) (Q47066) | ESCHERICHIA COLI | TOH0-1 BETA LACTAMASE |
| 2 | B (A) | 2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl)-2-oxo-2-{[(2S,3S)-1-oxo-3-(sulfoamino)butan-2-yl]amino}ethylidene]amino}oxy)-2-methylpropanoic acid | non-polymer | 437.4 | 1 | Chemie (AZR) | |||
| 3 | C, D, E, F, G (A) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 4 | H (A) | water | water | 18.0 | 506 | Chemie (HOH) |
Sequence modifications
A: 26 - 290 (UniProt: E1ANH6)
| PDB | External Database | Details |
|---|---|---|
| Ala 166 | Glu 169 | conflict |
| Asn 274 | Ser 275 | conflict |
| Asn 276 | Arg 277 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28117.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 917.8 | |
| All* | Total formula weight | 29035.5 |
