Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0008800 | molecular_function | beta-lactamase activity |
A | 0016787 | molecular_function | hydrolase activity |
A | 0017001 | biological_process | antibiotic catabolic process |
A | 0030655 | biological_process | beta-lactam antibiotic catabolic process |
A | 0046677 | biological_process | response to antibiotic |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE SO4 A 1001 |
Chain | Residue |
A | TRP229 |
A | PRO252 |
A | GLU254 |
A | ASN255 |
A | HIS256 |
A | PHE290 |
A | HOH2497 |
A | HOH2499 |
A | HOH2500 |
site_id | AC2 |
Number of Residues | 13 |
Details | BINDING SITE FOR RESIDUE SO4 A 1002 |
Chain | Residue |
A | LYS82 |
A | ALA198 |
A | ASN274 |
A | ASN276 |
A | ASP277 |
A | HOH2384 |
A | HOH2429 |
A | HOH2485 |
A | HOH2486 |
A | HOH2501 |
A | HOH2502 |
A | HOH2503 |
A | HOH2504 |
site_id | AC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 A 1003 |
Chain | Residue |
A | ALA52 |
A | ARG178 |
A | HOH2080 |
A | HOH2353 |
A | HOH2371 |
site_id | AC4 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 A 1005 |
Chain | Residue |
A | LYS88 |
A | HIS89 |
A | ASN92 |
A | HOH2195 |
A | HOH2199 |
A | HOH2205 |
site_id | AC5 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 A 1006 |
Chain | Residue |
A | GLU269 |
A | GLN270 |
A | HOH2376 |
A | HOH2460 |
A | HOH2481 |
A | HOH2505 |
A | HOH2506 |
site_id | AC6 |
Number of Residues | 16 |
Details | Binding site for Ligand AZR A 301 bound to SER A 70 |
Chain | Residue |
A | CYS69 |
A | SER70 |
A | ASN104 |
A | TYR105 |
A | SER130 |
A | ASN132 |
A | PRO167 |
A | ASN170 |
A | LYS234 |
A | THR235 |
A | GLY236 |
A | SER237 |
A | ASP240 |
A | HOH2452 |
A | HOH2453 |
A | HOH2457 |
Functional Information from PROSITE/UniProt
site_id | PS00146 |
Number of Residues | 16 |
Details | BETA_LACTAMASE_A Beta-lactamase class-A active site. FaMCSTsKvmaAAAVL |
Chain | Residue | Details |
A | PHE66-LEU81 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | ACT_SITE: Acyl-ester intermediate |
Chain | Residue | Details |
A | SER70 | |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | BINDING: |
Chain | Residue | Details |
A | LYS234 | |