5G0I
Crystal structure of Danio rerio HDAC6 CD1 and CD2 (linker cleaved) in complex with Nexturastat A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | HDAC6 | polymer | 809 | 89347.5 | 2 | UniProt (F8W4B7) Pfam (PF00850) | DANIO RERIO (ZEBRAFISH) | |
| 2 | C, D, M, N (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | E, F, G, H, O... (A, B) | POTASSIUM ION | non-polymer | 39.1 | 8 | Chemie (K) | |||
| 4 | I, J, S, T (A, B) | NEXTURASTAT A | non-polymer | 341.4 | 4 | Chemie (N4R) | |||
| 5 | K (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | L, U (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 7 | V, W (A, B) | water | water | 18.0 | 630 | Chemie (HOH) |
Sequence modifications
A, B: 25 - 831 (UniProt: F8W4B7)
| PDB | External Database | Details |
|---|---|---|
| Gly 23 | - | expression tag |
| Pro 24 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 178695.1 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 2099.6 | |
| All* | Total formula weight | 180794.7 |
