5FY0
Crystal structure of JmjC domain of human histone demethylase UTY in complex with L-malate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | HISTONE DEMETHYLASE UTY | polymer | 478 | 55006.4 | 2 | UniProt (O14607) Pfam (PF02373) Pfam (PF21322) Pfam (PF21326) | HOMO SAPIENS (HUMAN) | UBIQUITOUSLY-TRANSCRIBED TPR PROTEIN ON THE Y CHROMOSOME, U BIQUITOUSLY-TRANSCRIBED Y CHROMOSOME TETRATRICOPEPTIDE REPEAT PROTEIN |
| 2 | C, M (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 3 | D, N (A, B) | (2S)-2-hydroxybutanedioic acid | non-polymer | 134.1 | 2 | Chemie (LMR) | |||
| 4 | E, F, G, H, I... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 15 | Chemie (EDO) | |||
| 5 | L, W (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 6 | X, Y (A, B) | water | water | 18.0 | 594 | Chemie (HOH) |
Sequence modifications
A, B: 878 - 1347 (UniProt: O14607)
| PDB | External Database | Details |
|---|---|---|
| Met 877 | - | expression tag |
| Ala 1348 | - | expression tag |
| Glu 1349 | - | expression tag |
| Asn 1350 | - | expression tag |
| Leu 1351 | - | expression tag |
| Tyr 1352 | - | expression tag |
| Phe 1353 | - | expression tag |
| Gln 1354 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 110012.8 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 1439.9 | |
| All* | Total formula weight | 111452.7 |
