Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 4002 |
| Chain | Residue |
| A | CYS1278 |
| A | CYS1281 |
| A | CYS1305 |
| A | CYS1308 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 4002 |
| Chain | Residue |
| B | CYS1278 |
| B | CYS1281 |
| B | CYS1305 |
| B | CYS1308 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN B 2345 |
| Chain | Residue |
| B | GLU1095 |
| B | HIS1173 |
| B | HOH2130 |
| B | HOH2137 |
| B | LMR2346 |
| B | HIS1093 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN A 2345 |
| Chain | Residue |
| A | HIS1093 |
| A | GLU1095 |
| A | HIS1173 |
| A | HOH2142 |
| A | HOH2150 |
| A | LMR2346 |
| A | EDO2353 |
| site_id | AC5 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE LMR B 2346 |
| Chain | Residue |
| B | TYR1082 |
| B | LYS1084 |
| B | THR1090 |
| B | HIS1093 |
| B | ASN1103 |
| B | TRP1113 |
| B | HIS1173 |
| B | ASN1183 |
| B | HOH2123 |
| B | HOH2125 |
| B | HOH2137 |
| B | MN2345 |
| site_id | AC6 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE LMR A 2346 |
| Chain | Residue |
| A | TYR1082 |
| A | LYS1084 |
| A | THR1090 |
| A | HIS1093 |
| A | ASN1103 |
| A | TRP1113 |
| A | HIS1173 |
| A | VAL1175 |
| A | ASN1183 |
| A | HOH2137 |
| A | HOH2150 |
| A | MN2345 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 2347 |
| Chain | Residue |
| B | ILE967 |
| B | TRP968 |
| B | ARG969 |
| B | ASN1131 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 2347 |
| Chain | Residue |
| A | SER932 |
| A | THR933 |
| A | GLN986 |
| A | PRO1108 |
| A | ASN1182 |
| A | EDO2348 |
| A | EDO2352 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 2348 |
| Chain | Residue |
| A | PHE990 |
| A | HOH2073 |
| A | EDO2347 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 2349 |
| Chain | Residue |
| A | ARG1156 |
| A | HOH2004 |
| B | GLU999 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 2350 |
| Chain | Residue |
| A | HIS1267 |
| A | GLU1273 |
| A | HIS1276 |
| A | TYR1301 |
| site_id | BC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 2351 |
| Chain | Residue |
| A | GLY919 |
| A | GLY922 |
| A | PRO1161 |
| A | GLY1162 |
| A | ASP1163 |
| A | HOH2179 |
| A | HOH2306 |
| A | HOH2307 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 2348 |
| Chain | Residue |
| A | LYS895 |
| B | VAL1123 |
| B | ASP1126 |
| B | PHE1127 |
| B | HOH2280 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 2349 |
| Chain | Residue |
| B | PHE990 |
| B | PRO1108 |
| B | TRP1180 |
| B | HOH2073 |
| B | HOH2281 |
| B | EDO2350 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 2350 |
| Chain | Residue |
| B | THR933 |
| B | GLN986 |
| B | PRO1108 |
| B | ASN1182 |
| B | EDO2349 |
| site_id | BC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 2352 |
| Chain | Residue |
| A | LEU928 |
| A | GLY929 |
| A | SER932 |
| A | ILE1106 |
| A | GLY1107 |
| A | HOH2155 |
| A | EDO2347 |
| site_id | BC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 2351 |
| Chain | Residue |
| B | VAL1059 |
| B | VAL1060 |
| B | HOH2104 |
| B | HOH2114 |
| B | LEU1050 |
| B | ARG1058 |
| site_id | BC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 2353 |
| Chain | Residue |
| A | GLY1075 |
| A | GLU1095 |
| A | TRP1186 |
| A | ASN1187 |
| A | HOH2142 |
| A | MN2345 |
| site_id | CC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 2352 |
| Chain | Residue |
| B | HIS943 |
| B | ASP1036 |
| B | ASP1039 |
| B | HOH2038 |
| site_id | CC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 2353 |
| Chain | Residue |
| B | LYS1207 |
| B | CYS1281 |
| B | GLU1282 |
| B | VAL1283 |
| B | HOH2186 |
| site_id | CC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE EDO B 2354 |
| Chain | Residue |
| B | GLY1075 |
| B | GLN1080 |
| B | TYR1082 |
| B | GLU1095 |
| B | SER1101 |
| B | ASN1187 |
| B | HOH2122 |
| B | HOH2123 |
| B | HOH2130 |
| B | HOH2137 |
