5FX5
Novel inhibitors of human rhinovirus 3C protease
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | RHINOVIRUS 3C PROTEASE | polymer | 182 | 20125.8 | 1 | UniProt (P04936) Pfam (PF00548) | HUMAN RHINOVIRUS 2 (HRV2) | |
| 2 | B, C (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 3 | D (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 4 | E (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 5 | F (A) | ethyl (4R)-4-[[(2S,3R)-1-[(2S)-3-methyl-2-[(5-methyl-1,2-oxazol-3-yl)carbonylamino]butanoyl]-3-phenyl-pyrrolidin-2-yl]carbonylamino]-5-[(3S)-2-oxidanylidenepyrrolidin-3-yl]pentanoate | non-polymer | 609.7 | 1 | Chemie (HOV) | |||
| 6 | G (A) | water | water | 18.0 | 182 | Chemie (HOH) |
Sequence modifications
A: 1 - 180 (UniProt: P04936)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 20125.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1138.3 | |
| All* | Total formula weight | 21264.1 |
