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5FW5

Crystal structure of human G3BP1 in complex with Semliki Forest Virus nsP3-25 comprising two FGDF motives

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN 1polymer14015986.22UniProt (Q13283)
Pfam (PF02136)
HOMO SAPIENS (HUMAN)G3BP-1, ATP-DEPENDENT DNA HELICASE VIII, HDH VIII, GAP SH3 DOMAIN-BINDING PROTEIN 1, G3BP1
2C
(C)
NON-STRUCTURAL PROTEIN 3polymer252734.81UniProt (P08411)SEMLIKI FOREST VIRUS
3D, E, G, H
(A, B)
SULFATE IONnon-polymer96.14Chemie (SO4)
4F, I
(A, B)
ACETATE IONnon-polymer59.02Chemie (ACT)
5J, K, L, M
(B)
GLYCEROLnon-polymer92.14Chemie (GOL)
6N, O
(B)
POTASSIUM IONnon-polymer39.12Chemie (K)
7P, Q, R
(A, B, C)
waterwater18.0275Chemie (HOH)
Sequence modifications
A, B: 1 - 139 (UniProt: Q13283)
PDBExternal DatabaseDetails
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight34707.1
Non-Polymers*Number of molecules12
Total formula weight948.9
All*Total formula weight35656.0
*Water molecules are not included.

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PDB entries from 2025-12-10

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