5FV9
Crystal structure of GalNAc-T2 in complex with compound 16d
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | GALNAC-T2 | polymer | 571 | 64824.7 | 6 | UniProt (Q10471) Pfam (PF00535) Pfam (PF00652) | HOMO SAPIENS (HUMAN) | |
| 2 | G, GA, P, S, X... (A, F, B, C, D...) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 6 | Chemie (UDP) | |||
| 3 | AA, H, HA, O, T... (E, A, F, B, C...) | MANGANESE (II) ION | non-polymer | 54.9 | 6 | Chemie (MN) | |||
| 4 | CA, DA, EA, FA, I... (E, A, F, B, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 14 | Chemie (EDO) | |||
| 5 | L, M, MA, NA, W (A, F, C) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 6 | BA, IA, N (E, F, B) | [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl hydrogen (S)-{3-[(2R,3R,4R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]propyl}phosphonate | non-polymer | 512.4 | 3 | Chemie (Y6W) | |||
| 7 | OA, PA, QA, RA, SA... (A, B, C, D, E...) | water | water | 18.0 | 1633 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 571 (UniProt: Q10471)
| PDB | External Database | Details |
|---|---|---|
| Asp 516 | Asn 516 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 388948.2 | |
| Non-Polymers* | Number of molecules | 34 |
| Total formula weight | 5621.2 | |
| All* | Total formula weight | 394569.4 |
