5FV1

Crystal structure of hVEGF in complex with VK domain antibody

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (L, M)	VK DOMAIN ANTIBODY	polymer	108	12043.5	2		HOMO SAPIENS (HUMAN)
2	C, D (V, W)	VASCULAR ENDOTHELIAL GROWTH FACTOR A	polymer	116	13548.4	2	UniProt (P15692) Pfam (PF00341)	HOMO SAPIENS (HUMAN)	VEGF-A, VASCULAR PERMEABILITY FACTOR, VPF, VASCULAR ENDOTHE LIAL GROWTH FACTOR
3	E, F, G, H (L, M, V, W)	water	water		18.0	73	Chemie (HOH)

Sequence modifications

V, W: 1 - 110 (UniProt: P15692)

PDB	External Database	Details
His 111	-	expression tag
His 112	-	expression tag
His 113	-	expression tag
His 114	-	expression tag
His 115	-	expression tag
His 116	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	51184.0
All*	Total formula weight	51184.0

*Water molecules are not included.