5FTI
Crystal structure of the GluA2 K738M-T744K LBD in complex with glutamate (lithium form)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | GLUTAMATE RECEPTOR 2 | polymer | 291 | 32264.1 | 2 | UniProt (P19491) Pfam (PF10613) Pfam (PF00060) Pfam (PF00497) In PDB | RATTUS NORVEGICUS (NORWAY RAT) | GLUR-2, AMPA-SELECTIVE GLUTAMATE RECEPTOR 2, GLUR-B, GLUR-K2, GLUTAMATE RECEPTOR IONOTROPIC, AMPA 2, GLUA2 |
2 | A, B | GLUTAMIC ACID | non-polymer | 147.1 | 2 | Chemie (GLU) | |||
3 | A, B | LITHIUM ION | non-polymer | 6.9 | 2 | Chemie (LI) | |||
4 | A, B | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
5 | A, B | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
6 | water | water | 18.0 | 688 | Chemie (HOH) |
Sequence modifications
A, B: 383 - 506 (UniProt: P19491)
A, B: 632 - 775 (UniProt: P19491)
PDB | External Database | Details |
---|---|---|
Met 362 | - | expression tag |
His 363 | - | expression tag |
His 364 | - | expression tag |
His 365 | - | expression tag |
His 366 | - | expression tag |
His 367 | - | expression tag |
His 368 | - | expression tag |
His 369 | - | expression tag |
His 370 | - | expression tag |
Ser 371 | - | expression tag |
Ser 372 | - | expression tag |
Gly 373 | - | expression tag |
Leu 374 | - | expression tag |
Val 375 | - | expression tag |
Pro 376 | - | expression tag |
Arg 377 | - | expression tag |
Gly 378 | - | expression tag |
Ser 379 | - | expression tag |
Ala 380 | - | expression tag |
Met 381 | - | expression tag |
Gly 382 | - | expression tag |
Arg 389 | Gly 410 | engineered mutation |
Gly 390 | Leu 411 | engineered mutation |
Ala 391 | Glu 412 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly 555 | - | linker |
Thr 566 | - | linker |
Met 738 | Lys 759 | engineered mutation |
Lys 744 | Thr 765 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 64528.2 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 876.6 | |
All* | Total formula weight | 65404.8 |