5FS6
Crystal structure of the V243L mutant of human apoptosis inducing factor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | APOPTOSIS-INDUCING FACTOR 1, MITOCHONDRIAL | polymer | 515 | 56252.9 | 2 | UniProt (O95831) Pfam (PF00070) Pfam (PF14721) | HOMO SAPIENS (HUMAN) | PROGRAMMED CELL DEATH PROTEIN 8, APOPTOSIS INDUCING FACTOR |
| 2 | C, D (A, B) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 2 | Chemie (FAD) | |||
| 3 | E, F (B) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 2 | Chemie (TRS) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 907 | Chemie (HOH) |
Sequence modifications
A, B: 103 - 613 (UniProt: O95831)
| PDB | External Database | Details |
|---|---|---|
| Leu 614 | - | expression tag |
| Val 615 | - | expression tag |
| Pro 616 | - | expression tag |
| Arg 617 | - | expression tag |
| Leu 243 | Val 243 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 112505.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1815.4 | |
| All* | Total formula weight | 114321.2 |
