5FQO

Crystal structure of M. musculus protein arginine methyltransferase PRMT6 with SAH and magnesium

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	PROTEIN ARGININE N-METHYLTRANSFERASE 6	polymer	402	44356.0	1	UniProt (Q6NZB1) Pfam (PF13649) Pfam (PF22528)	MUS MUSCULUS (HOUSE MOUSE)	HISTONE-ARGININE N-METHYLTRANSFERASE PRMT6
2	B (A)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	1	Chemie (SAH)
3	C (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
4	D (A)	water	water		18.0	248	Chemie (HOH)

Sequence modifications

A: 1 - 378 (UniProt: Q6NZB1)

PDB	External Database	Details
Met -23	-	expression tag
Gly -22	-	expression tag
Ser -21	-	expression tag
Ser -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
Ser -13	-	expression tag
Ser -12	-	expression tag
Gly -11	-	expression tag
Thr -10	-	expression tag
Gly -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Leu 315	Phe 315	variant

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	44356.0
Non-Polymers*	Number of molecules	2
	Total formula weight	408.7
All*	Total formula weight	44764.7

*Water molecules are not included.