5FOB
Crystal Structure of Human Complement C3b in complex with Smallpox Inhibitor of Complement (SPICE)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | COMPLEMENT C3 BETA CHAIN | polymer | 645 | 71393.3 | 1 | UniProt (P01024) Pfam (PF17790) Pfam (PF01835) Pfam (PF17791) Pfam (PF17789) Pfam (PF07703) | HOMO SAPIENS (HUMAN) | C3 AND PZP-LIKE ALPHA-2-MACROGLOBULIN DOMAIN-CONTAINING PROTEIN 1 |
| 2 | B (B) | COMPLEMENT C3B ALPHA' CHAIN | polymer | 915 | 104074.1 | 1 | UniProt (P01024) Pfam (PF07677) Pfam (PF01759) Pfam (PF00207) Pfam (PF21406) Pfam (PF07678) Pfam (PF21308) | HOMO SAPIENS (HUMAN) | |
| 3 | C (C) | SMALLPOX INHIBITOR OF COMPLEMENT SPICE, D15L | polymer | 245 | 26868.2 | 1 | UniProt (Q76U65) Pfam (PF00084) | VARIOLA MAJOR VIRUS | |
| 4 | D (D) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G32152BH) | |||
| 5 | E (E) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 6 | F, GA, MA, PA, QA (A, B, C) | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
| 7 | AA, BA, CA, DA, EA... (B, A, C) | GLYCEROL | non-polymer | 92.1 | 24 | Chemie (GOL) | |||
| 8 | HA, Q (B, A) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 9 | IA, JA, KA, LA, R... (B, A) | IODIDE ION | non-polymer | 126.9 | 7 | Chemie (IOD) | |||
| 10 | RA, SA, TA (A, B, C) | water | water | 18.0 | 207 | Chemie (HOH) |
Sequence modifications
B: 749 - 1663 (UniProt: P01024)
| PDB | External Database | Details |
|---|---|---|
| Glu 1013 | Gln 1013 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 202335.7 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1157.1 | |
| Non-Polymers* | Number of molecules | 38 |
| Total formula weight | 3321.8 | |
| All* | Total formula weight | 206814.6 |
