5FN0
Crystal structure of Pseudomonas fluorescens kynurenine-3- monooxygenase (KMO) in complex with GSK180
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | KYNURENINE 3-MONOOXYGENASE | polymer | 461 | 50739.5 | 4 | UniProt (Q84HF5) | PSEUDOMONAS FLUORESCENS | PFKMO, KYNURENINE 3-HYDROXYLASE |
| 2 | E, G, I, K (A, B, C, D) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 4 | Chemie (FAD) | |||
| 3 | F, H, J, L (A, B, C, D) | 3-(5,6-DICHLORO-2-OXOBENZO[D]OXAZOL-3(2H)-YL)PROPANOIC ACID | non-polymer | 276.1 | 4 | Chemie (JHY) | |||
| 4 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 298 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 460 (UniProt: Q84HF5)
| PDB | External Database | Details |
|---|---|---|
| Ser 461 | Cys 461 | engineered mutation |
| Ser 252 | Cys 252 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 202958.1 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 4246.5 | |
| All* | Total formula weight | 207204.6 |
