5FLC
Architecture of human mTOR Complex 1 - 5.9 Angstrom reconstruction
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (1, 3) | SERINE/THREONINE-PROTEIN KINASE MTOR | polymer | 615 | 52357.7 | 2 | HOMO SAPIENS (HUMAN) | FK506-BINDING PROTEIN 12-RAPAMYCIN COMPLEX-ASSOCIATED PROTEIN 1, FKBP12-RAPAMYCIN COMPLEX-ASSOCIATED PROTEIN, MAMMALIAN TARGET OF RAPAMYCIN, MTOR, MECHANISTIC TARGET OF RAPAMYCIN, RAPAMYCIN AND FKBP12 TARGET 1, RAPAMYCIN TARGET PROTEIN 1 | |
| 2 | B, D (2, 4) | SERINE/THREONINE-PROTEIN KINASE MTOR | polymer | 365 | 31081.2 | 2 | HOMO SAPIENS (HUMAN) | FK506-BINDING PROTEIN 12-RAPAMYCIN COMPLEX-ASSOCIATED PROTEIN 1, FKBP12-RAPAMYCIN COMPLEX-ASSOCIATED PROTEIN, MAMMALIAN TARGET OF RAPAMYCIN, MTOR, MECHANISTIC TARGET OF RAPAMYCIN, RAPAMYCIN AND FKBP12 TARGET 1, RAPAMYCIN TARGET PROTEIN 1 | |
| 3 | E, I (A, E) | REGULATORY-ASSOCIATED PROTEIN OF MTOR | polymer | 1029 | 87590.0 | 2 | HOMO SAPIENS (HUMAN) | RAPTOR, P150 TARGET OF RAPAMYCIN (TOR)-SCAFFOLD PROTEIN | |
| 4 | F, J (B, F) | SERINE/THREONINE-PROTEIN KINASE MTOR | polymer | 1168 | 134036.6 | 2 | UniProt (P42345) Pfam (PF02259) Pfam (PF08771) Pfam (PF00454) Pfam (PF02260) | HOMO SAPIENS (HUMAN) | FK506-BINDING PROTEIN 12-RAPAMYCIN COMPLEX-ASSOCIATED PROTEIN 1, FKBP12-RAPAMYCIN COMPLEX-ASSOCIATED PROTEIN, MAMMALIAN TARGET OF RAPAMYCIN, MTOR, MECHANISTIC TARGET OF RAPAMYCIN, RAPAMYCIN A ND FKBP12 TARGET 1, RAPAMYCIN TARGET PROTEIN 1 |
| 5 | G, K (C, G) | FKBP | polymer | 107 | 9124.2 | 2 | SPODOPTERA FRUGIPERDA (FALL ARMYWORM) | ||
| 6 | H, L (D, H) | TARGET OF RAPAMYCIN COMPLEX SUBUNIT LST8 | polymer | 326 | 35910.1 | 2 | UniProt (Q9BVC4) Pfam (PF00400) | HOMO SAPIENS (HUMAN) | TORC SUBUNIT LST8, G PROTEIN BETA SUBUNIT-LIKE, GABLE, PROTEIN GBETAL, MAMMALIAN LETHAL WITH SEC13 PROTEIN 8, MLST8 |
| 7 | M, N (C, G) | RAPAMYCIN IMMUNOSUPPRESSANT DRUG | non-polymer | 914.2 | 2 | Chemie (RAP) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 700199.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1828.3 | |
| All* | Total formula weight | 702028.0 |
