5FJA
Cryo-EM structure of yeast RNA polymerase III at 4.7 A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC1 | polymer | 1460 | 162517.8 | 1 | UniProt (P04051) Pfam (PF04997) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) In PDB | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RNA POLYMERASE III SUBUNIT C1, DNA-DIRECTED RNA POLYMERASE III LARGEST SUBUNIT, RNA POLYMERASE III SUBUNIT C160, RNA POLYMERASE III |
| 2 | B | DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC2 | polymer | 1149 | 129629.4 | 1 | UniProt (P22276) Pfam (PF04567) Pfam (PF00562) Pfam (PF04560) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF04566) In PDB | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RNA POLYMERASE III SUBUNIT C2, C128, DNA-DIRECTED RNA POLYMERASE III 130 KDA POLYPEPTIDE, RNA POLYMERASE III |
| 3 | C | DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC1 | polymer | 335 | 37732.6 | 1 | UniProt (P07703) Pfam (PF01193) Pfam (PF01000) In PDB | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RNA POLYMERASES I AND III SUBUNIT AC1, C37, DNA-DIRECTED RNA POLYMERASES I AND III 40 KDA POLYPEPTIDE, AC40, C40, RNA POLYMERASE III |
| 4 | D | DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC9 | polymer | 161 | 18623.1 | 1 | UniProt (P47076) Pfam (PF03874) In PDB | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RNA POLYMERASE III SUBUNIT C9, RNA POLYMERASE III SUBUNIT C 17, RNA POLYMERASE III |
| 5 | E | DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1 | polymer | 215 | 25117.1 | 1 | UniProt (P20434) Pfam (PF03871) Pfam (PF01191) In PDB | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RNA POLYMERASES I, II, AND III SUBUNIT ABC1, ABC27, DNA-DIRECTED RNA POLYMERASES I, II, AND III 27 KDA POLYPEPTIDE, RNA POLYMERASE III |
| 6 | F | DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 2 | polymer | 155 | 17931.8 | 1 | UniProt (P20435) Pfam (PF01192) In PDB | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RNA POLYMERASES I, II, AND III SUBUNIT ABC2, ABC23, DNA-DIRECTED RNA POLYMERASES I, II, AND III 23 KDA POLYPEPTIDE, RNA POLYMERASE III |
| 7 | G | DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC8 | polymer | 212 | 24349.8 | 1 | UniProt (P35718) Pfam (PF03876) Pfam (PF08292) In PDB | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RNA POLYMERASE III SUBUNIT C8, DNA-DIRECTED RNA POLYMERASE III 25 KDA POLYPEPTIDE, RNA POLYMERASE III SUBUNIT C25, RNA POLYMERASE III |
| 8 | H | DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 3 | polymer | 146 | 16525.4 | 1 | UniProt (P20436) Pfam (PF03870) In PDB | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RNA POLYMERASES I, II, AND III SUBUNIT ABC3, ABC14.4, ABC14.5, DNA-DIRECTED RNA POLYMERASES I, II, AND III 14.5 KDA POLYPEPTIDE, RNA POLYMERASE III |
| 9 | I | DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC10 | polymer | 110 | 12525.1 | 1 | UniProt (Q04307) Pfam (PF02150) Pfam (PF01096) In PDB | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RNA POLYMERASE III SUBUNIT C10, DNA-DIRECTED RNA POLYMERASE S III 12.5 KDA POLYPEPTIDE, RNA POLYMERASE III SUBUNIT C11, RNA POLYMERASE III |
| 10 | J | DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 5 | polymer | 70 | 8290.7 | 1 | UniProt (P22139) Pfam (PF01194) In PDB | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RNA POLYMERASES I, II, AND III SUBUNIT ABC5, ABC10-BETA, ABC8, DNA-DIRECTED RNA POLYMERASES I, II, AND III 8.3 KDA POLYPEPTID POLYPEPTIDE, RNA POLYMERASE III |
| 11 | K | DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC2 | polymer | 142 | 16167.9 | 1 | UniProt (P28000) Pfam (PF13656) Pfam (PF01193) In PDB | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RNA POLYMERASES I AND III SUBUNIT AC2, AC19, DNA-DIRECTED RNA POLYMERASES I AND III 16 KDA POLYPEPTIDE, RPA19, RNA POLYMERASE III |
| 12 | L | DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 4 | polymer | 70 | 7730.0 | 1 | UniProt (P40422) Pfam (PF03604) In PDB | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RNA POLYMERASES I, II, AND III SUBUNIT ABC4, ABC10-ALPHA, RNA POLYMERASE III |
| 13 | M | DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC5 | polymer | 282 | 32178.1 | 1 | UniProt (P36121) Pfam (PF04801) In PDB | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RNA POLYMERASE III SUBUNIT C5, DNA-DIRECTED RNA POLYMERASE III 37 KDA POLYPEPTIDE, RNA POLYMERASE III SUBUNIT C37, RNA POLYMERASE III |
| 14 | N | DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC4 | polymer | 422 | 46751.5 | 1 | UniProt (P25441) Pfam (PF05132) In PDB | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RNA POLYMERASE III SUBUNIT C4, C53, DNA-DIRECTED RNA POLYMERASE III 47 KDA POLYPEPTIDE, RNA POLYMERASE III |
| 15 | O | DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC3 | polymer | 654 | 74112.8 | 1 | UniProt (P32349) Pfam (PF08221) Pfam (PF05645) Pfam (PF20912) In PDB | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RNA POLYMERASE III SUBUNIT C3, C82, DNA-DIRECTED III 74 KDA POLYPEPTIDE, C74, RNA POLYMERASE III |
| 16 | P | DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC6 | polymer | 317 | 36174.2 | 1 | UniProt (P32910) Pfam (PF05158) In PDB | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RNA POLYMERASE III SUBUNIT C6, C34, DNA-DIRECTED RNA POLYMERASE III 36 KDA POLYPEPTIDE, RNA POLYMERASE III |
| 17 | Q | DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC7 | polymer | 88 | 8987.3 | 1 | UniProt (P17890) In PDB | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RNA POLYMERASE III SUBUNIT C7, DNA-DIRECTED RNA POLYMERASE III 31 KDA POLYPEPTIDE, C31, RNA POLYMERASE III |
| 18 | A, B, I, J, L | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 17 |
| Total formula weight | 675344.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 392.5 | |
| All* | Total formula weight | 675737.0 |
