5FI1

Crystal Structure of the P-Rex1 DH/PH tandem in complex with Cdc42

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein,Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein	polymer	374	43066.6	1	UniProt (Q8TCU6) Pfam (PF00621) In PDB	Homo sapiens (Human)	PtdIns(3,4,5)-dependent Rac exchanger 1,PtdIns(3,4,5)-dependent Rac exchanger 1
2	B	Cell division control protein 42 homolog	polymer	194	21616.9	1	UniProt (P60953) Pfam (PF00071) In PDB	Homo sapiens (Human)	G25K GTP-binding protein

Sequence modifications

A: 38 - 201 (UniProt: Q8TCU6)

PDB	External Database	Details
Gly -2	-	expression tag
Glu -1	-	expression tag
Phe 0	-	expression tag

A: 202 - 408 (UniProt: Q8TCU6)
B: 1 - 191 (UniProt: P60953)

PDB	External Database	Details
Gly -2	-	expression tag
Glu -1	-	expression tag
Phe 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	64683.5
All*	Total formula weight	64683.5

*Water molecules are not included.