5FHZ

Human aldehyde dehydrogenase 1A3 complexed with NAD(+) and retinoic acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Aldehyde dehydrogenase family 1 member A3	polymer	529	58186.5	8	UniProt (P47895) Pfam (PF00171)	Homo sapiens (Human)	Aldehyde dehydrogenase 6,Retinaldehyde dehydrogenase 3,RalDH3
2	I, K, M, O, Q... (A, B, C, D, E...)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	8	Chemie (NAD)
3	J, L, N, P (A, B, C, D)	RETINOIC ACID	non-polymer		300.4	4	Chemie (REA) PubChem (23275881) PubChem (25145416) PubChem (445925) PubChem (87179195) PubChem (87519764) PubChem (87980058) PubChem (88439848) PubChem (88525859) PubChem (88604688) PubChem (5538) PubChem (444795) PubChem (449171) PubChem (5282379) PubChem (6336207) PubChem (6336229) PubChem (6419708) PubChem (6603983) PubChem (9796370) PubChem (9861147) PubChem (10881132) PubChem (12358677) PubChem (12358678) PubChem (12358679) PubChem (12358681) PubChem (134688661) PubChem (139597075) PubChem (145826768) PubChem (166478803)
4	AA, U, V, W, X... (H, A, B, C, D...)	water	water		18.0	63	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 1 - 512 (UniProt: P47895)

PDB	External Database	Details
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Leu -10	-	expression tag
Glu -9	-	expression tag
Ser -8	-	expression tag
Thr -7	-	expression tag
Ser -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Lys -3	-	expression tag
Lys -2	-	expression tag
Ala -1	-	expression tag
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	465492.2
Non-Polymers*	Number of molecules	12
	Total formula weight	6509.1
All*	Total formula weight	472001.4

*Water molecules are not included.