5FHZ

Human aldehyde dehydrogenase 1A3 complexed with NAD(+) and retinoic acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Aldehyde dehydrogenase family 1 member A3	polymer	529	58186.5	8	UniProt (P47895) Pfam (PF00171)	Homo sapiens (Human)	Aldehyde dehydrogenase 6,Retinaldehyde dehydrogenase 3,RalDH3
2	I, K, M, O, Q... (A, B, C, D, E...)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	8	Chemie (NAD)
3	J, L, N, P (A, B, C, D)	RETINOIC ACID	non-polymer		300.4	4	Chemie (REA)
4	AA, U, V, W, X... (H, A, B, C, D...)	water	water		18.0	63	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 1 - 512 (UniProt: P47895)

PDB	External Database	Details
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Leu -10	-	expression tag
Glu -9	-	expression tag
Ser -8	-	expression tag
Thr -7	-	expression tag
Ser -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Lys -3	-	expression tag
Lys -2	-	expression tag
Ala -1	-	expression tag
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	465492.2
Non-Polymers*	Number of molecules	12
	Total formula weight	6509.1
All*	Total formula weight	472001.4

*Water molecules are not included.