5FG6
Crystal structure of the bromodomain of human BRD1 (BRPF2) in complex with OF-1 chemical probe
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bromodomain-containing protein 1 | polymer | 128 | 14862.0 | 1 | UniProt (O95696) Pfam (PF00439) | Homo sapiens (Human) | BR140-like protein,Bromodomain and PHD finger-containing protein 2 |
| 2 | B, C, D, E (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 3 | F (A) | 4-bromanyl-~{N}-(6-methoxy-1,3-dimethyl-2-oxidanylidene-benzimidazol-5-yl)-2-methyl-benzenesulfonamide | non-polymer | 440.3 | 1 | Chemie (5XE) | |||
| 4 | G (A) | NICKEL (II) ION | non-polymer | 58.7 | 1 | Chemie (NI) | |||
| 5 | H (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 6 | I (A) | water | water | 18.0 | 190 | Chemie (HOH) |
Sequence modifications
A: 563 - 688 (UniProt: O95696)
| PDB | External Database | Details |
|---|---|---|
| Ser 561 | - | expression tag |
| Met 562 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14862.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 842.2 | |
| All* | Total formula weight | 15704.3 |
