5FG5
Crystal structure of the bromodomain of human BRPF1 in complex with PFI-4 chemical probe
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Peregrin | polymer | 116 | 13703.7 | 2 | UniProt (P55201) Pfam (PF00439) In PDB | Homo sapiens (Human) | Bromodomain and PHD finger-containing protein 1,Protein Br140 |
2 | A, B | ~{N}-(1,3-dimethyl-2-oxidanylidene-6-pyrrolidin-1-yl-benzimidazol-5-yl)-2-methoxy-benzamide | non-polymer | 380.4 | 2 | Chemie (5XF) | |||
3 | B | NITRATE ION | non-polymer | 62.0 | 1 | Chemie (NO3) | |||
4 | water | water | 18.0 | 252 | Chemie (HOH) |
Sequence modifications
A, B: 626 - 740 (UniProt: P55201)
PDB | External Database | Details |
---|---|---|
Ser 625 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 27407.4 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 822.9 | |
All* | Total formula weight | 28230.3 |