5FG5
Crystal structure of the bromodomain of human BRPF1 in complex with PFI-4 chemical probe
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 10 |
Details | binding site for residue 5XF A 801 |
Chain | Residue |
A | ILE635 |
A | HOH917 |
A | ILE652 |
A | GLU655 |
A | VAL657 |
A | PRO658 |
A | GLU661 |
A | ASN708 |
A | PHE714 |
A | HOH906 |
site_id | AC2 |
Number of Residues | 2 |
Details | binding site for residue NO3 B 801 |
Chain | Residue |
B | PRO632 |
B | PHE633 |
site_id | AC3 |
Number of Residues | 12 |
Details | binding site for residue 5XF B 802 |
Chain | Residue |
B | ILE635 |
B | LYS639 |
B | ASN651 |
B | ILE652 |
B | PHE653 |
B | GLU655 |
B | VAL657 |
B | PRO658 |
B | GLU661 |
B | ASN708 |
B | PHE714 |
B | HOH907 |
Functional Information from PROSITE/UniProt
site_id | PS00633 |
Number of Residues | 58 |
Details | BROMODOMAIN_1 Bromodomain signature. GniFsepvPlsevp..DYLdhIkkpMdfftMkqnleayr..Ylnfddfeedfnl.IvsNClkY |
Chain | Residue | Details |
A | GLY650-TYR707 |