5FG5
Crystal structure of the bromodomain of human BRPF1 in complex with PFI-4 chemical probe
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue 5XF A 801 |
| Chain | Residue |
| A | ILE635 |
| A | HOH917 |
| A | ILE652 |
| A | GLU655 |
| A | VAL657 |
| A | PRO658 |
| A | GLU661 |
| A | ASN708 |
| A | PHE714 |
| A | HOH906 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue NO3 B 801 |
| Chain | Residue |
| B | PRO632 |
| B | PHE633 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue 5XF B 802 |
| Chain | Residue |
| B | ILE635 |
| B | LYS639 |
| B | ASN651 |
| B | ILE652 |
| B | PHE653 |
| B | GLU655 |
| B | VAL657 |
| B | PRO658 |
| B | GLU661 |
| B | ASN708 |
| B | PHE714 |
| B | HOH907 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 58 |
| Details | BROMODOMAIN_1 Bromodomain signature. GniFsepvPlsevp..DYLdhIkkpMdfftMkqnleayr..Ylnfddfeedfnl.IvsNClkY |
| Chain | Residue | Details |
| A | GLY650-TYR707 |
