5FDO
Mcl-1 complexed with small molecule inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Induced myeloid leukemia cell differentiation protein Mcl-1 | polymer | 150 | 17150.6 | 4 | UniProt (Q07820) Pfam (PF00452) | Homo sapiens (Human) | Bcl-2-like protein 3,Bcl2-L-3,Bcl-2-related protein EAT/mcl1,mcl1/EAT |
| 2 | E, F, G, H (A, B, C, D) | 3-[3-(4-chloranyl-3,5-dimethyl-phenoxy)propyl]-~{N}-(phenylsulfonyl)-1~{H}-indole-2-carboxamide | non-polymer | 497.0 | 4 | Chemie (5X2) |
Sequence modifications
A, B, C, D: 172 - 320 (UniProt: Q07820)
| PDB | External Database | Details |
|---|---|---|
| Gly 171 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 68602.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1988.0 | |
| All* | Total formula weight | 70590.3 |
