5FBL

PI4KB in complex with Rab11 and the MI356 Inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Phosphatidylinositol 4-kinase beta,Phosphatidylinositol 4-kinase beta	polymer	572	65264.8	1	UniProt (Q9UBF8) Pfam (PF21245) Pfam (PF00454) In PDB	Homo sapiens (Human)	PtdIns 4-kinase beta,NPIK,PI4K92,PI4KB,PtdIns 4-kinase beta,NPIK,PI4K92,PI4KB
2	B	Ras-related protein Rab-11A	polymer	221	24828.0	1	UniProt (P62491) Pfam (PF00071) In PDB	Homo sapiens (Human)	Rab-11,YL8
3	A	~{N}-[2-[[6-chloranyl-3-(4-methoxy-3-morpholin-4-ylsulfonyl-phenyl)-2-methyl-imidazo[1,2-b]pyridazin-8-yl]amino]ethyl]ethanamide	non-polymer		523.0	1	Chemie (5W9)
4	B	5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE	non-polymer		539.2	1	Chemie (GSP)

Sequence modifications

A: 128 - 522 (UniProt: Q9UBF8)
A: 523 - 799 (UniProt: Q9UBF8)
B: 1 - 216 (UniProt: P62491)

PDB	External Database	Details
Gly -4	-	expression tag
Ala -3	-	expression tag
Met -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	90092.7
Non-Polymers*	Number of molecules	2
	Total formula weight	1062.3
All*	Total formula weight	91155.0

*Water molecules are not included.