5FBK
Crystal structure of the extracellular domain of human calcium sensing receptor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Extracellular calcium-sensing receptor | polymer | 568 | 64215.4 | 2 | UniProt (P41180) Pfam (PF01094) | Homo sapiens (Human) | CaSR,Parathyroid cell calcium-sensing receptor 1,PCaR1 |
| 2 | C, M (A, B) | CYCLOMETHYLTRYPTOPHAN | non-polymer | 216.2 | 2 | Chemie (TCR) | |||
| 3 | D, E, F, G, N... (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 8 | Chemie (NAG) | |||
| 4 | H, I, J, R, S... (A, B) | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) | |||
| 5 | K, U (A, B) | BICARBONATE ION | non-polymer | 61.0 | 2 | Chemie (BCT) | |||
| 6 | L, V, W (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 7 | X, Y (A, B) | water | water | 18.0 | 323 | Chemie (HOH) |
Sequence modifications
A, B: 20 - 541 (UniProt: P41180)
| PDB | External Database | Details |
|---|---|---|
| Met -26 | - | initiating methionine |
| Arg -25 | - | expression tag |
| Leu -24 | - | expression tag |
| Leu -23 | - | expression tag |
| Thr -22 | - | expression tag |
| Ala -21 | - | expression tag |
| Leu -20 | - | expression tag |
| Phe -19 | - | expression tag |
| Ala -18 | - | expression tag |
| Tyr -17 | - | expression tag |
| Phe -16 | - | expression tag |
| Ile -15 | - | expression tag |
| Val -14 | - | expression tag |
| Ala -13 | - | expression tag |
| Leu -12 | - | expression tag |
| Ile -11 | - | expression tag |
| Leu -10 | - | expression tag |
| Ala -9 | - | expression tag |
| Phe -8 | - | expression tag |
| Ser -7 | - | expression tag |
| Val -6 | - | expression tag |
| Ser -5 | - | expression tag |
| Ala -4 | - | expression tag |
| Lys -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Met -1 | - | expression tag |
| His 0 | - | expression tag |
| His 1 | - | expression tag |
| His 2 | - | expression tag |
| His 3 | - | expression tag |
| His 4 | - | expression tag |
| His 5 | - | expression tag |
| His 6 | - | expression tag |
| His 7 | - | expression tag |
| Ser 8 | - | expression tag |
| Ala 9 | - | expression tag |
| Trp 10 | - | expression tag |
| Ser 11 | - | expression tag |
| His 12 | - | expression tag |
| Pro 13 | - | expression tag |
| Gln 14 | - | expression tag |
| Phe 15 | - | expression tag |
| Glu 16 | - | expression tag |
| Lys 17 | - | expression tag |
| Glu 18 | - | expression tag |
| Phe 19 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 128430.8 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 2609.8 | |
| All* | Total formula weight | 131040.6 |
