5F9T
Crystal Structure of Streptococcus pneumoniae NanC, covalent complex with a fluorinated Neu5Ac derivative
Replaces: 4YW0Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Neuraminidase C | polymer | 659 | 73978.6 | 2 | UniProt (A0A0H2UQE4) Pfam (PF02973) Pfam (PF02012) Pfam (PF13088) UniProt (by SIFTS) (A0A0B7LH44) | Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) | Putative neuraminidase |
| 2 | C, F (A, B) | 5-acetamido-3,5-dideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid | non-polymer | 327.3 | 2 | Chemie (FSI) | |||
| 3 | D, G (A, B) | (2R,3R,4R,5R,6R)-5-acetamido-2,3-difluoro-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]tetrahydro-2H-pyran-2-carboxylic acid | non-polymer | 329.3 | 2 | Chemie (SFJ) | |||
| 4 | E (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 553 | Chemie (HOH) |
Sequence modifications
A, B: 83 - 740 (UniProt: A0A0H2UQE4)
| PDB | External Database | Details |
|---|---|---|
| Leu 741 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 147957.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1405.1 | |
| All* | Total formula weight | 149362.3 |
