5F92

Fumarate hydratase of Mycobacterium tuberculosis in complex with formate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Fumarate hydratase class II	polymer	495	52619.3	4	UniProt (P9WN92) Pfam (PF00206) Pfam (PF10415) UniProt (by SIFTS) (P9WN93)	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	Fumarase C
2	E, F, I, J (A, B)	FORMIC ACID	non-polymer		46.0	4	Chemie (FMT)
3	G, K (A, D)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
4	H (A)	TETRAETHYLENE GLYCOL	non-polymer		194.2	1	Chemie (PG4)
5	L, M, N, O (A, B, C, D)	water	water		18.0	1594	Chemie (HOH)

Sequence modifications

A, B, C, D: 2 - 474 (UniProt: P9WN92)

PDB	External Database	Details
Met -20	-	initiating methionine
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
Ser -13	-	expression tag
Ser -12	-	expression tag
Gly -11	-	expression tag
Val -10	-	expression tag
Asp -9	-	expression tag
Leu -8	-	expression tag
Gly -7	-	expression tag
Thr -6	-	expression tag
Glu -5	-	expression tag
Asn -4	-	expression tag
Leu -3	-	expression tag
Tyr -2	-	expression tag
Phe -1	-	expression tag
Gln 0	-	expression tag
Ser 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	210477.4
Non-Polymers*	Number of molecules	7
	Total formula weight	449.2
All*	Total formula weight	210926.6

*Water molecules are not included.