5F7O
Crystal structure of Mutant Q289L of adenosine/Methylthioadenosine phosphorylase from Schistosoma mansoni in complex with Adenine
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Methylthioadenosine phosphorylase | polymer | 320 | 35244.5 | 3 | UniProt (I0B503) Pfam (PF01048) In PDB | Schistosoma mansoni (Blood fluke) | |
2 | A, B | ADENINE | non-polymer | 135.1 | 2 | Chemie (ADE) | |||
3 | B, C | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
4 | water | water | 18.0 | 1058 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 299 (UniProt: I0B503)
PDB | External Database | Details |
---|---|---|
Met -20 | - | initiating methionine |
Gly -19 | - | expression tag |
Ser -18 | - | expression tag |
Ser -17 | - | expression tag |
His -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
Ser -10 | - | expression tag |
Ser -9 | - | expression tag |
Gly -8 | - | expression tag |
Leu -7 | - | expression tag |
Val -6 | - | expression tag |
Pro -5 | - | expression tag |
Arg -4 | - | expression tag |
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
His -1 | - | expression tag |
Met 0 | - | expression tag |
Leu 289 | Gln 289 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 105733.5 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 462.4 | |
All* | Total formula weight | 106195.9 |