5F6V
Crystal structure of Ubc9 (K48/K49A/E54A) complexed with Fragment 1 (biphenol from fragment cocktail screen)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | SUMO-conjugating enzyme UBC9 | polymer | 157 | 17725.4 | 1 | UniProt (P63279) Pfam (PF00179) | Homo sapiens (Human) | SUMO-protein ligase,Ubiquitin carrier protein 9,Ubiquitin carrier protein I,Ubiquitin-conjugating enzyme E2 I,Ubiquitin-protein ligase I,p18 |
| 2 | B (A) | 2-(2-hydroxyphenyl)phenol | non-polymer | 186.2 | 1 | Chemie (5VL) | |||
| 3 | C (A) | water | water | 18.0 | 228 | Chemie (HOH) |
Sequence modifications
A: 2 - 158 (UniProt: P63279)
| PDB | External Database | Details |
|---|---|---|
| Ala 48 | Lys 48 | engineered mutation |
| Ala 49 | Lys 49 | engineered mutation |
| Ala 54 | Glu 54 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17725.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 186.2 | |
| All* | Total formula weight | 17911.6 |
