5F5O

Crystal structure of Marburg virus nucleoprotein core domain bound to VP35 regulation peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E	Nucleoprotein	polymer	373	41691.4	3	UniProt (Q6UY69) Pfam (PF05505) In PDB	Lake Victoria marburgvirus (strain Ozolin-75) (MARV Marburg virus (strain South Africa/Ozolin/1975))	Nucleocapsid protein
2	B, D, F	Peptide from Polymerase cofactor VP35	polymer	29	3217.6	3	UniProt (Q6UY68) In PDB	Lake Victoria marburgvirus (strain Ozolin-75)
3	A, C	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
4		water	water		18.0	232	Chemie (HOH)

Sequence modifications

A, C, E: 19 - 370 (UniProt: Q6UY69)

PDB	External Database	Details
Met -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Ser 1	-	expression tag
His 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
Ser 8	-	expression tag
Ser 9	-	expression tag
Gly 10	-	expression tag
Leu 11	-	expression tag
Val 12	-	expression tag
Pro 13	-	expression tag
Arg 14	-	expression tag
Gly 15	-	expression tag
Ser 16	-	expression tag
His 17	-	expression tag
Met 18	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	134727.0
Non-Polymers*	Number of molecules	3
	Total formula weight	288.2
All*	Total formula weight	135015.2

*Water molecules are not included.