5F5I
Crystal Structure of human JMJD2A complexed with KDOOA011340
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Lysine-specific demethylase 4A | polymer | 363 | 42293.1 | 2 | UniProt (O75164) Pfam (PF02375) Pfam (PF02373) | Homo sapiens (Human) | JmjC domain-containing histone demethylation protein 3A,Jumonji domain-containing protein 2A |
| 2 | C, G (A, B) | NICKEL (II) ION | non-polymer | 58.7 | 2 | Chemie (NI) | |||
| 3 | D, H (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | E, I (A, B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | F, J (A, B) | 2-[[(phenylmethyl)amino]methyl]pyridine-4-carboxylic acid | non-polymer | 242.3 | 2 | Chemie (5V1) | |||
| 6 | K, L (A, B) | water | water | 18.0 | 152 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 359 (UniProt: O75164)
| PDB | External Database | Details |
|---|---|---|
| Tyr -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Gln -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 84586.2 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 924.9 | |
| All* | Total formula weight | 85511.1 |
