5F5C
Crystal Structure of human JMJD2D complexed with KDOPP7
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Lysine-specific demethylase 4D | polymer | 346 | 40017.3 | 1 | UniProt (Q6B0I6) Pfam (PF02375) Pfam (PF02373) | Homo sapiens (Human) | JmjC domain-containing histone demethylation protein 3D,Jumonji domain-containing protein 2D |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | NICKEL (II) ION | non-polymer | 58.7 | 1 | Chemie (NI) | |||
| 4 | D, E, F, G, K (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 5 | H, I, J (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 6 | L (A) | 8-[[(phenylmethyl)amino]methyl]-1~{H}-pyrido[3,4-d]pyrimidin-4-one | non-polymer | 266.3 | 1 | Chemie (5V3) | |||
| 7 | M (A) | water | water | 18.0 | 411 | Chemie (HOH) |
Sequence modifications
A: 1 - 342 (UniProt: Q6B0I6)
| PDB | External Database | Details |
|---|---|---|
| Tyr -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Gln -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40017.3 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 988.9 | |
| All* | Total formula weight | 41006.3 |
