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5F5C

Crystal Structure of human JMJD2D complexed with KDOPP7

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ALysine-specific demethylase 4Dpolymer34640017.31UniProt (Q6B0I6)
Pfam (PF02375)
Pfam (PF02373)
In PDB
Homo sapiens (Human)JmjC domain-containing histone demethylation protein 3D,Jumonji domain-containing protein 2D
2AZINC IONnon-polymer65.41Chemie (ZN)
3ANICKEL (II) IONnon-polymer58.71Chemie (NI)
4A1,2-ETHANEDIOLnon-polymer62.15Chemie (EDO)
5ASULFATE IONnon-polymer96.13Chemie (SO4)
6A8-[[(phenylmethyl)amino]methyl]-1~{H}-pyrido[3,4-d]pyrimidin-4-onenon-polymer266.31Chemie (5V3)
7waterwater18.0411Chemie (HOH)
Sequence modifications
A: 1 - 342 (UniProt: Q6B0I6)
PDBExternal DatabaseDetails
Tyr -3-expression tag
Phe -2-expression tag
Gln -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight40017.3
Non-Polymers*Number of molecules11
Total formula weight988.9
All*Total formula weight41006.3
*Water molecules are not included.

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PDB entries from 2024-04-24

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