5F25
Crystal structure of the BRD9 bromodomain in complex with compound 4.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | BRD9 | polymer | 123 | 14249.8 | 2 | UniProt (Q9H8M2) Pfam (PF00439) | Homo sapiens (human) | BRD9, DKFZp434D0711, DKFZp686L0539, LAVS3040, PRO9856 |
| 2 | C, D (A, B) | 4-(1,5-dimethyl-6-oxidanylidene-pyridin-3-yl)benzamide | non-polymer | 242.3 | 2 | Chemie (5TU) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 306 | Chemie (HOH) |
Sequence modifications
A, B: 14 - 134 (UniProt: Q9H8M2)
| PDB | External Database | Details |
|---|---|---|
| Ser 12 | - | expression tag |
| Met 13 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28499.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 484.5 | |
| All* | Total formula weight | 28984.1 |
