5F25
Crystal structure of the BRD9 bromodomain in complex with compound 4.
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue 5TU A 201 |
| Chain | Residue |
| A | PHE44 |
| A | PHE45 |
| A | VAL49 |
| A | ILE53 |
| A | ALA54 |
| A | TYR99 |
| A | ASN100 |
| A | TYR106 |
| A | HOH304 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue 5TU B 201 |
| Chain | Residue |
| A | LYS119 |
| A | HOH352 |
| B | PHE44 |
| B | PHE45 |
| B | VAL49 |
| B | ALA54 |
| B | ASN100 |
| B | TYR106 |
| B | HOH301 |
| B | HOH392 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Region: {"description":"Histone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding","evidences":[{"source":"PubMed","id":"26365797","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Site: {"description":"Histone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding","evidences":[{"source":"PubMed","id":"26365797","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
