5F0L
Structure of retromer VPS26-VPS35 subunits bound to SNX3 and DMT1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Vacuolar protein sorting-associated protein 35 | polymer | 462 | 53288.3 | 1 | UniProt (Q96QK1) Pfam (PF03635) In PDB | Homo sapiens (Human) | hVPS35,Maternal-embryonic 3,Vesicle protein sorting 35 |
2 | B | Vacuolar protein sorting-associated protein 26A | polymer | 317 | 37164.8 | 1 | UniProt (O75436) Pfam (PF03643) In PDB | Homo sapiens (Human) | Vesicle protein sorting 26A,hVPS26 |
3 | C | Sorting nexin-3 | polymer | 167 | 19193.8 | 1 | UniProt (O60493) Pfam (PF00787) In PDB | Homo sapiens (Human) | Protein SDP3 |
4 | D | Natural resistance-associated macrophage protein 2 | polymer | 24 | 2660.0 | 1 | UniProt (P49281) In PDB | Homo sapiens (Human) | NRAMP 2,Divalent cation transporter 1,Divalent metal transporter 1,DMT-1,Solute carrier family 11 member 2 |
5 | A, C, B | SULFATE ION | non-polymer | 96.1 | 10 | Chemie (SO4) | |||
6 | A, C, B | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
7 | B, A, C | 1,2-ETHANEDIOL | non-polymer | 62.1 | 18 | Chemie (EDO) |
Sequence modifications
A: 14 - 470 (UniProt: Q96QK1)
C: 1 - 162 (UniProt: O60493)
PDB | External Database | Details |
---|---|---|
Gly 9 | - | expression tag |
Ala 10 | - | expression tag |
Met 11 | - | expression tag |
Gly 12 | - | expression tag |
Ser 13 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -4 | - | expression tag |
Ala -3 | - | expression tag |
Met -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 112306.9 | |
Non-Polymers* | Number of molecules | 34 |
Total formula weight | 2630.4 | |
All* | Total formula weight | 114937.3 |