5F0C
Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium tuberculosis in complex with compound 4 at 1.87A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HTH-type transcriptional regulator EthR | polymer | 228 | 25259.3 | 1 | UniProt (P9WMC0) Pfam (PF00440) Pfam (PF21313) UniProt (by SIFTS) (P9WMC1) | Mycobacterium tuberculosis CDC1551 | |
| 2 | B (A) | 3-cyclopentyl-~{N}-(3-piperidin-1-ylphenyl)propanamide | non-polymer | 300.4 | 1 | Chemie (5TE) | |||
| 3 | C, D (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | E (A) | water | water | 18.0 | 35 | Chemie (HOH) |
Sequence modifications
A: 2 - 216 (UniProt: P9WMC0)
| PDB | External Database | Details |
|---|---|---|
| Met -3 | - | initiating methionine |
| Asp -2 | - | expression tag |
| Ile -1 | - | expression tag |
| Glu 0 | - | expression tag |
| Phe 1 | - | expression tag |
| Gly 217 | - | expression tag |
| Ser 218 | - | expression tag |
| His 219 | - | expression tag |
| His 220 | - | expression tag |
| His 221 | - | expression tag |
| His 222 | - | expression tag |
| His 223 | - | expression tag |
| His 224 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 25259.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 492.6 | |
| All* | Total formula weight | 25751.8 |
