5F03
TRYPTASE B2 IN COMPLEX WITH 5-(3-Aminomethyl-phenoxymethyl)-3-[3-(2-chloro-pyridin-3-ylethynyl)-phenyl]-oxazolidin-2-one; compound with trifluoro-acetic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Tryptase beta-2 | polymer | 245 | 27491.4 | 2 | UniProt (P20231) Pfam (PF00089) UniProt (by SIFTS) (Q15661) | Homo sapiens (Human) | Tryptase-2,Tryptase II |
| 2 | C, D (A, B) | (5~{S})-5-[[3-(aminomethyl)phenoxy]methyl]-3-[3-[2-(2-chloranylpyridin-3-yl)ethynyl]phenyl]-1,3-oxazolidin-2-one | non-polymer | 433.9 | 2 | Chemie (5TA) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 689 | Chemie (HOH) |
Sequence modifications
A, B: 16 - 246 (UniProt: P20231)
| PDB | External Database | Details |
|---|---|---|
| Lys 113 | Asn 132 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 54982.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 867.8 | |
| All* | Total formula weight | 55850.6 |
