5EZ0
CRYSTAL STRUCTURE OF THE PTPN4 PDZ DOMAIN COMPLEXED WITH THE PDZ BINDING MOTIF OF THE MITOGEN ACTIVATED PROTEIN KINASE P38GAMMA.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Tyrosine-protein phosphatase non-receptor type 4 | polymer | 107 | 11694.4 | 4 | UniProt (P29074) Pfam (PF00595) | Homo sapiens (Human) | Protein-tyrosine phosphatase MEG1,PTPase-MEG1 |
| 2 | E, F, G, H (E, F, G, H) | Mitogen-activated protein kinase 12 | polymer | 11 | 1275.5 | 4 | UniProt (B5MDL5) | Homo sapiens | Mitogen-activated protein kinase 12,isoform CRA_a |
| 3 | I, J (D, G) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | K, L, M, N, O... (A, B, C, D, E...) | water | water | 18.0 | 95 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 499 - 604 (UniProt: P29074)
E, F, G, H: 5 - 13 (UniProt: B5MDL5)
| PDB | External Database | Details |
|---|---|---|
| Gly 498 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 3 | - | expression tag |
| Trp 4 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 51879.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 192.1 | |
| All* | Total formula weight | 52071.4 |
