5EXI

Crystal structure of M. tuberculosis lipoyl synthase at 2.28 A resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Lipoyl synthase	polymer	331	36939.9	1	UniProt (P9WK91) Pfam (PF16881) Pfam (PF04055)	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	Lip-syn,LS,Lipoate synthase,Lipoic acid synthase,Sulfur insertion protein LipA
2	B, C (A)	IRON/SULFUR CLUSTER	non-polymer		351.6	2	Chemie (SF4)
3	D (A)	(2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL	non-polymer		154.3	1	Chemie (DTV)
4	E (A)	water	water		18.0	216	Chemie (HOH)

Sequence modifications

A: 1 - 311 (UniProt: P9WK91)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	36939.9
Non-Polymers*	Number of molecules	3
	Total formula weight	857.5
All*	Total formula weight	37797.4

*Water molecules are not included.