5EXI
Crystal structure of M. tuberculosis lipoyl synthase at 2.28 A resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0009107 | biological_process | lipoate biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016992 | molecular_function | lipoate synthase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051536 | molecular_function | iron-sulfur cluster binding |
| A | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue SF4 A 401 |
| Chain | Residue |
| A | CYS81 |
| A | CYS85 |
| A | CYS88 |
| A | ARG192 |
| A | PHE195 |
| A | DTV403 |
| A | HOH502 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue SF4 A 402 |
| Chain | Residue |
| A | ASN62 |
| A | ILE63 |
| A | CYS66 |
| A | THR73 |
| A | ARG290 |
| A | SER292 |
| A | TYR293 |
| A | CYS55 |
| A | CYS60 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue DTV A 403 |
| Chain | Residue |
| A | GLY122 |
| A | LEU155 |
| A | SF4401 |
| A | HOH502 |
| A | HOH541 |
| A | HOH594 |
| A | HOH637 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00206, ECO:0000269|PubMed:27506792, ECO:0007744|PDB:5EXI, ECO:0007744|PDB:5EXJ |
| Chain | Residue | Details |
| A | CYS55 | |
| A | CYS60 | |
| A | CYS66 | |
| A | SER292 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00206, ECO:0000269|PubMed:27506792, ECO:0007744|PDB:5EXI, ECO:0007744|PDB:5EXJ, ECO:0007744|PDB:5EXK |
| Chain | Residue | Details |
| A | CYS81 | |
| A | CYS85 | |
| A | CYS88 |
