5EX0
Crystal structure of human SMYD3 in complex with a MAP3K2 peptide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Histone-lysine N-methyltransferase SMYD3 | polymer | 431 | 49541.5 | 1 | UniProt (Q9H7B4) Pfam (PF00856) Pfam (PF01753) In PDB | Homo sapiens (Human) | SET and MYND domain-containing protein 3,Zinc finger MYND domain-containing protein 1 |
2 | D | MAP3K2 peptide | polymer | 10 | 1085.2 | 1 | UniProt (by SIFTS) (Q9Y2U5) In PDB | Homo sapiens | |
3 | A | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
4 | A | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
5 | A | ACETIC ACID | non-polymer | 60.1 | 2 | Chemie (ACY) | |||
6 | water | water | 18.0 | 117 | Chemie (HOH) |
Sequence modifications
A: 1 - 428 (UniProt: Q9H7B4)
PDB | External Database | Details |
---|---|---|
Ser -2 | - | expression tag |
Glu -1 | - | expression tag |
Phe 0 | - | expression tag |
Asn 13 | Lys 13 | engineered mutation |
Arg 140 | Lys 140 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 50626.7 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 700.7 | |
All* | Total formula weight | 51327.4 |