5EWI

Crystal Structure of the Human Fab VRC38.01, an HIV-1 V1V2-Directed Neutralizing Antibody Isolated from Donor N90

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (H)	VRC38.01 Heavy Chain	polymer	236	25151.2	1	UniProt (Q6N089) Pfam (PF07686) Pfam (PF07654)	Homo sapiens
2	B (L)	VRC38.01 Light Chain	polymer	220	24123.9	1	UniProt (P01834) Pfam (PF07654)	Homo sapiens
3	C, D (H, L)	water	water		18.0	566	Chemie (HOH)

Sequence modifications

H: 1 - 105 (PDB: 5EWI)
H: 106 - 218 (UniProt: Q6N089)

PDB	External Database	Details
Gly 219	-	expression tag
Leu 220	-	expression tag
Glu 221	-	expression tag
Val 222	-	expression tag
Leu 223	-	expression tag
Phe 224	-	expression tag
Gln 225	-	expression tag

L: 1 - 108 (PDB: 5EWI)
L: 109 - 214 (UniProt: P01834)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	49275.1
All*	Total formula weight	49275.1

*Water molecules are not included.