5EWF
Ternary complex of human DNA polymerase eta inserting rCTP opposite an 8-Oxodeoxyguanosine Lesion
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | DNA polymerase eta | polymer | 435 | 48617.7 | 1 | UniProt (Q9Y253) Pfam (PF00817) Pfam (PF21704) Pfam (PF11799) In PDB | Homo sapiens (Human) | RAD30 homolog A,Xeroderma pigmentosum variant type protein |
2 | T | DNA (5'-D(*CP*AP*TP*(8OG)P*AP*TP*GP*AP*CP*GP*CP*T)-3') | polymer | 12 | 3678.4 | 1 | synthetic construct | ||
3 | P | DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3') | polymer | 8 | 2426.6 | 1 | synthetic construct | ||
4 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
5 | A | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
6 | T | CYTIDINE-5'-TRIPHOSPHATE | non-polymer | 483.2 | 1 | Chemie (CTP) | |||
7 | water | water | 18.0 | 387 | Chemie (HOH) |
Sequence modifications
A: 1 - 432 (UniProt: Q9Y253)
PDB | External Database | Details |
---|---|---|
Gly -2 | - | expression tag |
Pro -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 54722.7 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 615.3 | |
All* | Total formula weight | 55338.1 |