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5EW4

Crystal structure of C9ORF72 Antisense CCCCGG repeat RNA associated with Lou Gehrig's disease and frontotemporal dementia, crystallized with Sr2+

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
RNA (5'-R(*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*GP*GP*CP*CP*CP*C)-3')polymer226909.22Homo sapiens
2C, D, H, I, J...
(A, B)
POTASSIUM IONnon-polymer39.19Chemie (K)
3E
(B)
STRONTIUM IONnon-polymer87.61Chemie (SR)
4F, G
(B)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
5O
(B)
CHLORIDE IONnon-polymer35.51Chemie (CL)
6P, Q
(A, B)
waterwater18.0162Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight13818.4
Non-Polymers*Number of molecules13
Total formula weight523.6
All*Total formula weight14341.9
*Water molecules are not included.

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PDB entries from 2025-10-29

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