5EV3

Structure III of Intact U2AF65 Recognizing the 3' Splice Site Signal

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Splicing factor U2AF 65 kDa subunit	polymer	201	21970.0	1	UniProt (P26368) Pfam (PF00076)	Homo sapiens (Human)	U2 auxiliary factor 65 kDa subunit,hU2AF65,U2 snRNP auxiliary factor large subunit
2	B (B)	DNA/RNA (5'-R(P*UP*U)-D(P*U)-R(P*UP*U)-D(P*(BRU)P*UP*U)-3')	polymer	8	2419.3	1		synthetic construct
3	C, D (A, B)	water	water		18.0	263	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	24389.3
All*	Total formula weight	24389.3

*Water molecules are not included.