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5EV2

Structure II of Intact U2AF65 Recognizing the 3' Splice Site Signal

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Splicing factor U2AF 65 kDa subunitpolymer20121970.01UniProt (P26368)
Pfam (PF00076)
Homo sapiens (Human)U2 auxiliary factor 65 kDa subunit,hU2AF65,U2 snRNP auxiliary factor large subunit
2B
(B)
DNA (5'-R(P*UP*U)-D(P*UP*U)-R(P*U)-D(P*UP*(BRU)P*U)-3')polymer82403.31Synthetic Construct
3C
(A)
1,4-DIETHYLENE DIOXIDEnon-polymer88.11Chemie (DIO)
4D
(A)
TRIETHYLENE GLYCOLnon-polymer150.21Chemie (PGE)
5E
(A)
DI(HYDROXYETHYL)ETHERnon-polymer106.11Chemie (PEG)
6F, G
(A, B)
waterwater18.0203Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight24373.3
Non-Polymers*Number of molecules3
Total formula weight344.4
All*Total formula weight24717.7
*Water molecules are not included.

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PDB entries from 2025-06-18

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