5ERD
Crystal structure of human Desmoglein-2 ectodomain
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Desmoglein-2 | polymer | 559 | 62584.0 | 2 | UniProt (Q14126) Pfam (PF00028) In PDB | Homo sapiens (Human) | Cadherin family member 5,HDGC |
2 | C, D, G | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
3 | E | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G32152BH) | |||
4 | F, H, I | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
5 | B, A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
6 | B, A | alpha-D-mannopyranose | non-polymer | 180.2 | 6 | Chemie (MAN) | |||
7 | B, A | CALCIUM ION | non-polymer | 40.1 | 22 | Chemie (CA) | |||
8 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
9 | water | water | 18.0 | 192 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 553 (UniProt: Q14126)
PDB | External Database | Details |
---|---|---|
His 554 | - | expression tag |
His 555 | - | expression tag |
His 556 | - | expression tag |
His 557 | - | expression tag |
His 558 | - | expression tag |
His 559 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 125168.1 | |
Branched | Number of molecules | 7 |
Total formula weight | 3765.5 | |
Non-Polymers* | Number of molecules | 32 |
Total formula weight | 2688.3 | |
All* | Total formula weight | 131621.9 |