5EMZ

Crystal structure of K48-linked diubiquitin with F45W mutation in the proximal unit

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E (A, C, E)	Polyubiquitin-B	polymer	76	8604.8	3	UniProt (P0CG47) Pfam (PF00240)	Homo sapiens (Human)
2	B, D, F (B, D, F)	Polyubiquitin-B	polymer	76	8615.9	3	UniProt (P0CG47) Pfam (PF00240)	Homo sapiens (Human)
3	G, H, I, J (B, D, E)	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
4	K, L, M, N, O... (A, B, C, D, E...)	water	water		18.0	561	Chemie (HOH)

Sequence modifications

A, C, E: 1 - 76 (UniProt: P0CG47)

PDB	External Database	Details
Arg 48	Lys 48	conflict

B, D, F: 1 - 76 (UniProt: P0CG47)

PDB	External Database	Details
Trp 45	Phe 45	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	51662.1
Non-Polymers*	Number of molecules	4
	Total formula weight	384.3
All*	Total formula weight	52046.4

*Water molecules are not included.